Much needed deep dive on Alzheimer’s disease (AD) prevention tomorrow with my good friend and collaborator, Richard Isaacson. Glad we were able to address a bunch of AD questions, though I think we only scratched the surface.

On a different note, I listened to a fantastic episode of The Tim Ferriss Show: #338: Howard Marks — How to Invest with Clear Thinking. I’ve been a big fan of Marks ever since I read “The Most Important Thing,” published in 2011. I think I’ve read it two or three times, actually.

The thing I like so much about his writing (I also read his newsletter, which I recommend everyone subscribe to) is that he writes about decision-making, probability, risk, and uncertainty in the absence of complete information better than almost anyone, and certainly better than anyone in medicine. So ironically, while Marks applies these insights to financial investments, many of the same principles apply to the way we should treat our health. Sadly, this is so far from the way medicine is practiced today. Marks’ writing has probably had a greater impact on my thinking around ‘Medicine 3.0’ (a concept I will expand on in the future) than anyone else.

Lastly, can someone confirm if the Surgeon General needs to be an actual medical doctor (apparently a Supreme Court Justice does not need a law degree)? If not, I would like to nominate Howards Marks for the job.

– Peter

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