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The gold standard for testing longevity drugs: the Interventions Testing Program

Ep. #148 with Richard Miller, M.D., Ph.D.

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A masterclass on insulin resistance—molecular mechanisms and clinical implications

Ep. #140 with Gerald Shulman M.D., Ph.D.

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Alzheimer’s disease prevention—patient and doctor perspectives

Ep. #138 with Lauren Miller Rogen and Richard Isaacson, M.D.

Guest Episode

Q&A on Alzheimer’s disease drug therapy with Dr. Richard Isaacson

Ep. #2

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An expert perspective on COVID-19 vaccines

Ep. #137 with Paul Offit, M.D.

AMA

Body composition methods tour de force, insulin resistance, and Topo Chico

Ep. #136 (AMA #17)

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Preventing cardiovascular disease and the risk of too much exercise

Ep. #134 with James O'Keefe, M.D.

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The latest insights into cardiovascular disease and lipidology

Ep. #129 with Thomas Dayspring, M.D., FACP, FNLA

AMA

Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more

Ep. #124 (AMA #15)

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Rapamycin and metformin—longevity, immune enhancement, and COVID-19

Ep. #123 with Joan Mannick, M.D. & Nir Barzilai, M.D.

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Why we're losing the war on cancer

Ep. #121 with Azra Raza, M.D.

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Part II of II: Ketosis for cancer and chronic disease and the effect of ketosis on female health

Ep. #120 with Dom D'Agostino, Ph.D.

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Rapamycin, mTOR inhibition, and the biology of aging

Ep. #118 with Lloyd Klickstein M.D., Ph.D.

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Insights from a coronavirus expert on COVID-19

Ep. #117 with Stanley Perlman, M.D., Ph.D.

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Part I of II: Ketogenic diet, exogenous ketones, and exercise

Ep. #116 with Dom D'Agostino, Ph.D.

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COVID framework: How does this thing end?

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A masterclass in immunology, monoclonal antibodies, and vaccine strategies for COVID-19

Ep. #115 with David Watkins, Ph.D.

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Autophagy, fasting, and promising new cancer therapies

Ep. #114 with Eileen White, Ph.D.

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How cellular senescence influences aging, and what we can do about it

Ep. #112 with Ned David, Ph.D.

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Cancer metabolism, cancer therapies, and the discovery of PI3K

Ep. #110 with Lewis Cantley, Ph.D.

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Looking back on the first 99 episodes: Strong Convictions, Loosely Held

Ep. #103

AMA

Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more

Ep. #53 (AMA #6)