Centenarians—people who have survived to the age of 100—appear to have genes that provide natural resilience to aging. The data on centenarians are all observational, not experimental, so we can’t truly infer cause and effect. But by understanding centenarian genetics, which turns out to account for most of their remarkable longevity, we can infer which strategies the rest of us can employ to try to reap the same benefits.
By studying exactly how certain genetic variants provide benefit, we learn a very important lesson from these masters of longevity: They don’t live longer with disease; they live longer without disease. It’s from this observation that we derive a key principle in extending lifespan: to delay death, we must delay the onset of chronic disease as long as possible, not figure out ways to live longer with chronic disease.
Below is a compilation of past clips and podcasts specifically discussing centenarians and how to train for, what I like to call, the “Centenarian Olympics.”
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