Weekly Newsletter Archives - Peter Attia https://peterattiamd.com/category/weekly-newsletter/ Fri, 13 Dec 2024 17:06:56 +0000 en-US hourly 1 https://peterattiamd.com/wp-content/uploads/2023/04/cropped-apple-icon-32x32.png Weekly Newsletter Archives - Peter Attia https://peterattiamd.com/category/weekly-newsletter/ 32 32 A causal link between obesity and autoimmune disease https://peterattiamd.com/obesity-and-autoimmune-disease/ Sat, 08 Mar 2025 12:00:00 +0000 https://peterattiamd.com/?p=33000 A Mendelian randomization study provides compelling evidence that obesity may directly trigger autoimmune conditions

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]]> Concerning links between human papillomavirus (HPV) infection and male infertility https://peterattiamd.com/hpv-and-male-infertility/ Sat, 01 Mar 2025 12:00:00 +0000 https://peterattiamd.com/?p=32958 New results add to mounting evidence that high-risk HPV types negatively impact male fertility, underscoring the importance of vaccination in both sexes

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]]> A common nasal decongestant appears to be ineffective, so what alternatives exist? https://peterattiamd.com/nasal-decongestants/ Sat, 22 Feb 2025 12:00:00 +0000 https://peterattiamd.com/?p=32368 Despite a long history of use for decongestion, oral phenylephrine may soon disappear from cold and allergy medications due to a lack of efficacy.

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]]> How can the process of drug development be improved? https://peterattiamd.com/drug-development/ Sat, 15 Feb 2025 12:00:00 +0000 https://peterattiamd.com/?p=32314 Insights as to why so many drug candidates fail to make it through the development pipeline, and how certain strategies might help

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]]> Compounding effects of multiple metabolic conditions on cardiovascular risk https://peterattiamd.com/compounding-effects-of-metabolic-conditions-on-cardiovascular-risk/ Sat, 08 Feb 2025 12:00:00 +0000 https://peterattiamd.com/?p=32238 Recent evidence reveals that the combination of liver disease and type 2 diabetes has a multiplicative effect on cardiovascular disease and mortality

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]]> Unlocking the potential of migraine medications for endometriosis treatment https://peterattiamd.com/migraine-medications-for-endometriosis-treatment/ Sat, 01 Feb 2025 12:00:00 +0000 https://peterattiamd.com/?p=32159 Recent mouse studies indicate that FDA-approved CGRP blockers might offer a new treatment option for a condition affecting millions

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]]> Sleepless nights? Try boosting your physical activity level https://peterattiamd.com/exercise-for-improving-sleep/ Sat, 25 Jan 2025 12:00:00 +0000 https://peterattiamd.com/?p=31968 Even light-intensity exercise can help to improve sleep among those with insomnia

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]]> A nuanced and multifaceted approach to longevity research https://peterattiamd.com/beyond-randomized-controlled-trials/ Sat, 18 Jan 2025 12:00:00 +0000 https://peterattiamd.com/?p=31885 While randomized controlled trials remain the gold standard, understanding their limitations is crucial for advancing longevity science

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]]> A link between antihypertensive medications and fall risk reminds us to take precautions https://peterattiamd.com/fall-risk-and-antihypertensive-drugs/ Sat, 11 Jan 2025 12:00:00 +0000 https://peterattiamd.com/?p=31656 A recent study highlights the association between blood pressure medications and risk of falls and fall-related injuries, but we can take steps to offset the danger

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]]> The endless possibilities of living well in your marginal decade https://peterattiamd.com/marginal-decade-spotlights/ Sat, 04 Jan 2025 12:00:00 +0000 https://peterattiamd.com/?p=31493 A spotlight on a few inspirational people doing amazing things in their 80s, 90s, and beyond 

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]]> Using “atomic habits” to reach your health goals https://peterattiamd.com/atomic-habits-for-health-goals/ Sat, 28 Dec 2024 12:00:00 +0000 https://peterattiamd.com/?p=31321 A special end-of-year newsletter on how you can apply James Clear’s laws of behavior change to a few of the actionable steps we learned about on The Drive in 2024

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]]> Research Worth Sharing, December 2024 Edition https://peterattiamd.com/research-worth-sharing-december-2024/ Sat, 21 Dec 2024 12:00:00 +0000 https://peterattiamd.com/?p=31292 Type 2 diabetes in youths, extending organ viability, preventative ovary removal, “dark genome” therapeutics, and vascular impacts on physical decline

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]]> When caution becomes concerning: the relationship between health anxiety and mortality https://peterattiamd.com/health-anxiety-and-mortality/ https://peterattiamd.com/health-anxiety-and-mortality/#comments Sat, 14 Dec 2024 12:00:00 +0000 https://peterattiamd.com/?p=31214 Health awareness exists on a spectrum in which both extremes can be damaging to health and well-being

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]]> https://peterattiamd.com/health-anxiety-and-mortality/feed/ 2 A rational look at a sensationalized sugar study https://peterattiamd.com/sugar-restriction-in-early-life/ https://peterattiamd.com/sugar-restriction-in-early-life/#comments Sat, 07 Dec 2024 12:00:00 +0000 https://peterattiamd.com/?p=31019 A recent study has triggered alarm over the finding that restricting sugar in the first 1000 days of life protects against diabetes and hypertension in later life, but this conclusion hardly constitutes reliable advice

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]]> https://peterattiamd.com/sugar-restriction-in-early-life/feed/ 7 Oldies-But-Goodies, December 2024 Edition https://peterattiamd.com/email-roundup-december-2024/ https://peterattiamd.com/email-roundup-december-2024/#comments Sat, 30 Nov 2024 12:00:00 +0000 https://peterattiamd.com/?p=30729 A collection of past newsletters on topics including hearing loss prevention, a randomized trial on exercise and lifespan, using a cognitive bias to improve goal achievement, air pollution, and the impact of dietary protein on muscle protein synthesis

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]]> https://peterattiamd.com/email-roundup-december-2024/feed/ 6 Shingles and brain health: an emerging link or healthy user bias? https://peterattiamd.com/shingles-and-brain-health/ https://peterattiamd.com/shingles-and-brain-health/#comments Sat, 23 Nov 2024 12:00:00 +0000 https://peterattiamd.com/?p=30639 Several research articles have been circulating in the news, prompting excitement about the supposed ability of the shingles vaccine to prevent cognitive decline, but is there a causal link?

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]]> https://peterattiamd.com/shingles-and-brain-health/feed/ 9 Calming the concern over exercise duration and coronary artery calcification https://peterattiamd.com/exercise-intensity-and-cac/ https://peterattiamd.com/exercise-intensity-and-cac/#comments Sat, 16 Nov 2024 12:00:00 +0000 https://peterattiamd.com/?p=30398 A recent study reported positive correlations between exercise duration and CAC, but causality – and relevance to risk of cardiovascular events – is not established

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]]> https://peterattiamd.com/exercise-intensity-and-cac/feed/ 21 Radical extension of the human lifespan, science fiction or reality? https://peterattiamd.com/lifespan-extension/ https://peterattiamd.com/lifespan-extension/#comments Sat, 09 Nov 2024 12:00:58 +0000 https://peterattiamd.com/?p=28606 Humanity may be reaching the limits of lifespan extension that are possible through treatment of chronic disease, but the door is still open for future advances in aging biology itself

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]]> https://peterattiamd.com/lifespan-extension/feed/ 1 Failure of resveratrol to improve metabolic health is another nail in the coffin for the alleged “anti-aging” compound https://peterattiamd.com/resveratrol-and-metabolic-health/ Sat, 26 Oct 2024 11:00:12 +0000 https://peterattiamd.com/?p=28072 A recent meta-analysis of randomized trials assessed the performance of resveratrol in improving various metrics of metabolic health

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]]> Beyond the headlines: evaluating exercise as an equivalent to medication for the treatment of depression and anxiety https://peterattiamd.com/exercise-versus-medication-for-depression-and-anxiety/ Sat, 19 Oct 2024 11:00:52 +0000 https://peterattiamd.com/?p=27205 Popular media has circulated news of a study allegedly showing that exercise is preferable to medication as a treatment for anxiety and depression, but is this interpretation justified?

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]]> Research Worth Sharing, October 2024 Edition https://peterattiamd.com/research-worth-sharing-october-2024/ Sat, 12 Oct 2024 16:00:29 +0000 https://peterattiamd.com/?p=27037 Using biofeedback to reach weight loss goals, preventing falls with exercise, the impact of social support on stress eating, and an atlas of data on changes related to muscle aging

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]]> Do humans age in distinct rapid bursts instead of gradually over time? https://peterattiamd.com/is-human-aging-gradual/ Sat, 05 Oct 2024 11:00:41 +0000 https://peterattiamd.com/?p=26783 A recent study makes use of multi-omics data to establish patterns of human aging, but results have dubious relevance on an individual scale

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]]> High-intensity interval training and cognitive function in older adults: promising but limited findings https://peterattiamd.com/hiit-and-cognitive-function/ Sat, 28 Sep 2024 11:00:56 +0000 https://peterattiamd.com/?p=26590 A new study indicates that HIIT may help delay or even reverse age-related declines in memory and learning, but this exercise modality remains just one aspect of a well-balanced regimen.

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]]> Could plasma protein levels be a surrogate for VO2 max testing as a measure of cardiorespiratory fitness? https://peterattiamd.com/proteomics-and-cardiorespiratory-fitness/ Sat, 21 Sep 2024 11:00:00 +0000 https://peterattiamd.com/?p=26198 A proteomics model may provide an alternative method for estimating risk of mortality and chronic disease

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