Hormones Archives - Peter Attia

Does hormone replacement therapy impact dementia risk?

Peter Attia — Sat, 29 Jun 2024 11:00:13 +0000

A recent case-control study reports that menopausal hormone therapy is associated with increased risk of dementia, but results have little relevance for modern clinical practice

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Do high protein diets increase cancer risk?

Peter Attia — Wed, 12 Jun 2024 14:00:00 +0000

Is there any merit to the idea that consuming more protein increases one’s risk of developing or dying from cancer?

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Is the frequency of menopausal symptoms an early barometer for later-in-life brain health?

Peter Attia — Sat, 28 Oct 2023 11:00:37 +0000

More than “bothersome”: Frequent menopausal hot flashes during sleep are associated with greater white matter hyperintensity volume

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The cases for and against dietary protein for healthy aging

Peter Attia — Wed, 26 Jul 2023 22:29:42 +0000

An endeavor to settle the debate of high- vs. low-protein diets for increasing lifespan and healthspan

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#260 ‒ Men’s Sexual Health: why it matters, what can go wrong, and how to fix it | Mohit Khera, M.D., M.B.A., M.P.H.

Peter Attia — Mon, 26 Jun 2023 08:45:36 +0000

“Clinicians don't ask about it. Patients are embarrassed to ask about it. And that's the suffering in silence.” —Mohit Khera

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#259 – Women’s sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D.

Peter Attia — Mon, 19 Jun 2023 08:45:34 +0000

"I can't tell you how many women soldier on either avoiding sex or in pain because they don't either know or feel validated to seek treatment." —Sharon Parish

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Does carbohydrate load impact the balance between fat storage and oxidation?

Peter Attia — Sat, 10 Jun 2023 11:00:45 +0000

A study investigated the effects of different dietary levels of carbohydrates on mitochondrial respiration, but mechanistic conclusions are premature.

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#256 ‒ The endocrine system: exploring thyroid, adrenal, and sex hormones | Peter Attia, M.D.

Peter Attia — Mon, 29 May 2023 08:45:44 +0000

In this special episode of The Drive, Peter provides a comprehensive overview of the various endocrine systems: the thyroid system, the adrenal system, and the sex hormone system (for both men and women). He walks through the basic biology and the feedback cycles that regulate the production of these hormones and discusses the various options…

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#253 ‒ Hormone replacement therapy and the Women’s Health Initiative: re-examining the results, the link to breast cancer, and weighing the risk vs reward of HRT | JoAnn Manson, M.D.

Peter Attia — Mon, 08 May 2023 08:45:18 +0000

“It’s so important for women to understand that the absolute risks of these hormones are much lower in early menopause than in later menopause.” —JoAnn Manson

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#222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D.

Peter Attia — Mon, 12 Sep 2022 08:45:12 +0000

“It's really important that we be willing to change our beliefs about nutrition and other aspects of health as more data comes in.” —Matt Kaeberlein

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The five main tools for managing blood glucose numbers

Peter Attia — Tue, 16 Aug 2022 13:00:17 +0000

This clip is from AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions, originally released on August 23, 2021.

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#215 – The gut-brain connection | Michael Gershon, M.D.

Peter Attia — Mon, 25 Jul 2022 08:45:05 +0000

“The reason I call it “The Second Brain” is that, like the brain in the head, the nervous system of the gut is able to function and control reflexes and behavior independently of any influence from the brain or spinal cord.” —Michael Gershon

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#214 – AMA #37: Bone health—everything you need to know

Peter Attia — Mon, 18 Jul 2022 08:45:55 +0000

“The bones are mechanical sensory entities that are going to remodel in proportion to how much mechanical stress they're under…so lifting heavy stuff matters.” —Peter Attia

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#212 – The neuroscience of obesity | Stephan Guyenet, Ph.D.

Peter Attia — Mon, 27 Jun 2022 08:45:27 +0000

“This system works better at protecting against fat loss than it does against fat gain.” —Stephan Guyenet

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#203 – AMA #34: What Causes Heart Disease?

Peter Attia — Mon, 18 Apr 2022 08:45:38 +0000

“Not everybody dies from atherosclerosis, but… everybody dies with it.” — Peter Attia

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How alcohol disrupts sleep and contributes to Alzheimer’s disease

Peter Attia — Tue, 29 Mar 2022 23:00:27 +0000

This audio clip is from our “Ask Me Anything” with sleep expert, Matthew Walker (Part I of III), originally released on June 17, 2019. If you’re a member, you can now listen to this full episode on your private RSS feed or on our website. If you are not a member, learn more about the how to become a…

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Stress, Cortisol, and Sleep Deprivation: An Awful Feedback Loop

Peter Attia — Mon, 14 Mar 2022 23:15:22 +0000

This audio clip is from our “Ask Me Anything” with sleep expert, Matthew Walker (Part I of III), originally released on June 17, 2019. In this clip, Peter and Matthew Walker discuss the impact sleep deprivation can have on your stress levels, and how stress can also impact your sleep. If you’re a member, you…

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Peter Attia on the connection between stress and insulin resistance

Peter Attia — Wed, 23 Feb 2022 00:00:51 +0000

This clip is from “Ask Me Anything” (AMA) episode #17, originally released on November 9, 2020. If you’re a member, you can now listen to this full episode on your private RSS feed or on our website. If you are not a member, learn more about the how to become a member and the benefits here.

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#196 – AMA #32: Exercise, squats, deadlifts, BFR, and TRT

Peter Attia — Mon, 21 Feb 2022 09:45:52 +0000

“You have to differentiate between signal and noise. . .it's easy to say testosterone causes heart disease just like it's easy to say estrogen causes breast cancer. But if you're actually going to go through all of the data. . .I think it becomes very difficult to make that case.” —Peter Attia

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#194 – How fructose drives metabolic disease | Rick Johnson, M.D.

Peter Attia — Mon, 07 Feb 2022 09:45:46 +0000

“Fructose turns out to have been meant to be this wonderful system for survival, but in our culture with the amount of sugar in foods that we are eating (that either provide sugar or can be turned into fructose), this pathway has become hazardous.” —Rick Johnson

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#180 – AMA #28: All things testosterone and testosterone replacement therapy

Peter Attia — Mon, 18 Oct 2021 08:45:30 +0000

“There were countless other studies to look at, but they all basically point in the same direction, which is testosterone replacement therapy improves lean mass, reduces fat mass, improves strength.” —Peter Attia

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#124 – AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more

Peter Attia — Mon, 17 Aug 2020 09:45:29 +0000

As a follow up to AMA #14 where Peter explained his framework for analyzing labs, this “Ask Me Anything” (AMA) episode focuses on a number of real-world case studies exploring metabolic dysregulation, low testosterone, menopause, hypothyroidism, elevated uric acid, and more. From the examples discussed, you can follow along how our clinical team goes about…

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#120 – AMA with Dom D’Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health

Peter Attia — Mon, 20 Jul 2020 09:45:22 +0000

"The function of the mitochondria and mitochondrial health are the ultimate mitigator of neurodegenerative diseases...just by reducing the potential for reactive oxygen species related damage." — Dom D’Agostino

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#110 – Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K

Peter Attia — Mon, 11 May 2020 09:45:17 +0000

"If I get a result that suddenly doesn't make sense, to me that's more exciting. . .if you figure out why it didn't work and what was wrong, then that's where most breakthroughs come from." — Lew Cantley

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