Risks - Peter Attia

A causal link between obesity and autoimmune disease

Peter Attia — Sat, 08 Mar 2025 12:00:00 +0000

A Mendelian randomization study provides compelling evidence that obesity may directly trigger autoimmune conditions

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#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4

Peter Attia — Mon, 03 Mar 2025 05:15:00 +0000

“You need to tackle the foe [type 2 diabetes] by addressing more than one leg of the stool at a time.” —Peter Attia

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Concerning links between human papillomavirus (HPV) infection and male infertility

Peter Attia — Sat, 01 Mar 2025 12:00:00 +0000

New results add to mounting evidence that high-risk HPV types negatively impact male fertility, underscoring the importance of vaccination in both sexes

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#337 – Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D.

Peter Attia — Mon, 24 Feb 2025 05:15:00 +0000

“The pathophysiology will always tell you the truth.” —Ralph DeFronzo

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#336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

Peter Attia — Mon, 17 Feb 2025 05:15:00 +0000

“It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

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Compounding effects of multiple metabolic conditions on cardiovascular risk

Peter Attia — Sat, 08 Feb 2025 12:00:00 +0000

Recent evidence reveals that the combination of liver disease and type 2 diabetes has a multiplicative effect on cardiovascular disease and mortality

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#334 – Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D.

Peter Attia — Mon, 03 Feb 2025 05:15:00 +0000

“Cholesterol is almost certainly the most important molecule in the brain.” —Tom Dayspring

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#332 – AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk

Peter Attia — Mon, 20 Jan 2025 05:15:00 +0000

"As food and beverages undergo more and more processing, it accumulates more and more plastics, probably another argument for limiting processed foods." —Peter Attia

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All things blood pressure: from measurement to management

Peter Attia — Wed, 15 Jan 2025 16:00:00 +0000

Hypertension is often called the “silent killer.” This guide covers how to monitor blood pressure, who’s at highest risk, and how best to manage it.

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A link between antihypertensive medications and fall risk reminds us to take precautions

Peter Attia — Sat, 11 Jan 2025 12:00:00 +0000

A recent study highlights the association between blood pressure medications and risk of falls and fall-related injuries, but we can take steps to offset the danger

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Research Worth Sharing, December 2024 Edition

Peter Attia — Sat, 21 Dec 2024 12:00:00 +0000

Type 2 diabetes in youths, extending organ viability, preventative ovary removal, “dark genome” therapeutics, and vascular impacts on physical decline

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#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more

Peter Attia — Mon, 16 Dec 2024 09:00:00 +0000

In this special episode of The Drive, Peter tackles a wide range of listener questions submitted over the past year. The discussion spans essential topics such as exercise—covering grip strength, traveling workouts, and why Peter doesn’t consider exercise an ideal weight-loss strategy—and the top biomarkers everyone should track. He also explores promising new longevity research,…

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When caution becomes concerning: the relationship between health anxiety and mortality

Peter Attia — Sat, 14 Dec 2024 12:00:00 +0000

Health awareness exists on a spectrum in which both extremes can be damaging to health and well-being

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A rational look at a sensationalized sugar study

Peter Attia — Sat, 07 Dec 2024 12:00:00 +0000

A recent study has triggered alarm over the finding that restricting sugar in the first 1000 days of life protects against diabetes and hypertension in later life, but this conclusion hardly constitutes reliable advice

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Oldies-But-Goodies, December 2024 Edition

Peter Attia — Sat, 30 Nov 2024 12:00:00 +0000

A collection of past newsletters on topics including hearing loss prevention, a randomized trial on exercise and lifespan, using a cognitive bias to improve goal achievement, air pollution, and the impact of dietary protein on muscle protein synthesis

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Shingles and brain health: an emerging link or healthy user bias?

Peter Attia — Sat, 23 Nov 2024 12:00:00 +0000

Several research articles have been circulating in the news, prompting excitement about the supposed ability of the shingles vaccine to prevent cognitive decline, but is there a causal link?

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Calming the concern over exercise duration and coronary artery calcification

Peter Attia — Sat, 16 Nov 2024 12:00:00 +0000

A recent study reported positive correlations between exercise duration and CAC, but causality – and relevance to risk of cardiovascular events – is not established

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#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3

Peter Attia — Mon, 11 Nov 2024 09:45:29 +0000

“I suspect that that will be the challenge of the next decade or two. It'll be less about what is technically possible and more about what is ethically defensible.” —Peter Attia

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Radical extension of the human lifespan, science fiction or reality?

Peter Attia — Sat, 09 Nov 2024 12:00:58 +0000

Humanity may be reaching the limits of lifespan extension that are possible through treatment of chronic disease, but the door is still open for future advances in aging biology itself

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#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.

Peter Attia — Mon, 04 Nov 2024 09:45:31 +0000

“I still believe that a nutritional approach to weight loss without physical activity or exercise prescribed is not a good strategy. We should implement both and try to have people enjoying the exercise.” —Eric Ravussin

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#323 – CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.

Peter Attia — Mon, 28 Oct 2024 08:45:13 +0000

“One of the promises of gene editing is that it can provide a single treatment that is a cure for the disease.” —Feng Zhang

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#322 – Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.

Peter Attia — Mon, 21 Oct 2024 08:45:51 +0000

“Bone is a ‘use it or lose it’ tissue.” —Belinda Beck

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#321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D.

Peter Attia — Mon, 14 Oct 2024 08:45:48 +0000

“When we do things intentionally that are physically or mentally challenging for us, our body senses injury and up regulates feel good neurotransmitters. . .so we get our dopamine indirectly by paying for it upfront.” —Anna Lembke

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#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) – efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape

Peter Attia — Mon, 07 Oct 2024 08:45:03 +0000

"If you're taking these drugs, really, really pay attention to your protein consumption and your resistance training. . .that's obviously going to be an important part of being on the right side of that body composition curve.” — Peter Attia

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