Metabolic health Archives - Peter Attia https://peterattiamd.com/category/nutritional-biochemistry/metabolic-health/ Mon, 10 Mar 2025 03:33:27 +0000 en-US hourly 1 https://peterattiamd.com/wp-content/uploads/2023/04/cropped-apple-icon-32x32.png Metabolic health Archives - Peter Attia https://peterattiamd.com/category/nutritional-biochemistry/metabolic-health/ 32 32 #338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4 https://peterattiamd.com/qps4/ Mon, 03 Mar 2025 05:15:00 +0000 https://peterattiamd.com/?p=32932 You need to tackle the foe [type 2 diabetes] by addressing more than one leg of the stool at a time.” —Peter Attia

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#337 – Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D. https://peterattiamd.com/ralphdefronzo/ Mon, 24 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32876 The pathophysiology will always tell you the truth.” —Ralph DeFronzo

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#336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more https://peterattiamd.com/ama68/ Mon, 17 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32335 It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

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#331 ‒ Optimizing endurance performance: metrics, nutrition, lactate, and more insights from elite performers | Olav Aleksander Bu (Pt. 2) https://peterattiamd.com/olavaleksanderbu2/ Mon, 13 Jan 2025 05:15:00 +0000 https://peterattiamd.com/?p=31776 Sometimes it makes it more universally easy to understand if we think of what kind of sport we do as a function of intensity and duration.” —Olav Aleksander Bu

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#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more https://peterattiamd.com/specialama/ Mon, 16 Dec 2024 09:00:00 +0000 https://peterattiamd.com/?p=31196 In this special episode of The Drive, Peter tackles a wide range of listener questions submitted over the past year. The discussion spans essential topics such as exercise—covering grip strength, traveling workouts, and why Peter doesn’t consider exercise an ideal weight-loss strategy—and the top biomarkers everyone should track. He also explores promising new longevity research,…

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328 – AMA #66: Optimizing nutrition for health and longevity: myth of a “best” diet, complexities of nutrition science, and practical steps for building a sustainable diet https://peterattiamd.com/ama66/ Mon, 09 Dec 2024 09:00:00 +0000 https://peterattiamd.com/?p=31036 “There is no discipline of science or engineering for which our magnitude of certainty is so high relative to such poor quality data.” —Peter Attia

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#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D. https://peterattiamd.com/ericravussin/ https://peterattiamd.com/ericravussin/#comments Mon, 04 Nov 2024 09:45:31 +0000 https://peterattiamd.com/?p=28379 I still believe that a nutritional approach to weight loss without physical activity or exercise prescribed is not a good strategy. We should implement both and try to have people enjoying the exercise.” —Eric Ravussin

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#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) – efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape https://peterattiamd.com/ama64/ https://peterattiamd.com/ama64/#comments Mon, 07 Oct 2024 08:45:03 +0000 https://peterattiamd.com/?p=26802 "If you're taking these drugs, really, really pay attention to your protein consumption and your resistance training. . .that's obviously going to be an important part of being on the right side of that body composition curve.” — Peter Attia

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#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D. https://peterattiamd.com/davidallison2/ https://peterattiamd.com/davidallison2/#comments Mon, 19 Aug 2024 08:45:11 +0000 https://peterattiamd.com/?p=25662 I think we really need a radically different public health paradigm.” —David Allison

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#313 – AMA #62: Protein’s impact on appetite and weight management, and uric acid’s link to disease and how to manage levels https://peterattiamd.com/ama62/ https://peterattiamd.com/ama62/#comments Mon, 12 Aug 2024 08:45:11 +0000 https://peterattiamd.com/?p=25622 "The body responds in pretty significant ways to alterations in protein availability.” —Peter Attia

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#311 ‒ Longevity 101: a foundational guide to Peter’s frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more https://peterattiamd.com/longevity101/ https://peterattiamd.com/longevity101/#comments Mon, 29 Jul 2024 08:45:32 +0000 https://peterattiamd.com/?p=25544 I would say three-quarters of the benefits you can get towards a longer life, come solely from pursuing better health.” —Peter Attia

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#304 – NEW: Introducing quarterly podcast summaries – Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more https://peterattiamd.com/qps1/ https://peterattiamd.com/qps1/#comments Mon, 03 Jun 2024 08:45:16 +0000 https://peterattiamd.com/?p=25206 Getting a high VO2 max and being very strong are very hard to do. They take a long time. Everybody can do them, but they can't be done quickly and easily, so therefore, they are the tip of the spear.” —Peter Attia

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#300 – Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise? https://peterattiamd.com/ep-300-exercise-nutrition-fasting-more/ https://peterattiamd.com/ep-300-exercise-nutrition-fasting-more/#comments Mon, 06 May 2024 08:45:12 +0000 https://peterattiamd.com/?p=25063 The probability that having a high VO2 max, high muscle mass, and high muscle strength are going to increase the length of your life and improve the quality of your life. . .is so high that to act in disregard of that is irresponsible.” —Peter Attia

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#299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D. https://peterattiamd.com/lucvanloon/ https://peterattiamd.com/lucvanloon/#comments Mon, 22 Apr 2024 08:45:32 +0000 https://peterattiamd.com/?p=24954 "It's the exercise that makes you respond way more to the same or less amount of protein that you ingest.” —Luc van Loon

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“DNA diets” are still a long way off from offering an easier route to weight loss https://peterattiamd.com/dna-diets-for-weight-loss/ Sat, 16 Mar 2024 11:00:53 +0000 https://peterattiamd.com/?p=24765 A recent study reports that leveraging genetics to inform diet choice is ineffective in promoting weight loss beyond the effects of calorie restriction alone

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Optimizing protein quantity, distribution, and quality https://peterattiamd.com/protein-intake-distribution/ https://peterattiamd.com/protein-intake-distribution/#comments Wed, 06 Mar 2024 12:00:00 +0000 https://peterattiamd.com/?p=24703 Maximizing muscle protein synthesis is more than a matter of daily protein intake. How we distribute protein throughout the day matters, as does protein quality.

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#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D. https://peterattiamd.com/colleencutcliffe/ https://peterattiamd.com/colleencutcliffe/#comments Mon, 18 Dec 2023 09:45:06 +0000 https://peterattiamd.com/?p=22433 You start out almost like a blank slate, you get a lot more diverse, and then as we age, you start to lose that diversity and therefore some key functions in the microbiome.” —Colleen Cutcliffe

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Sugar substitutes: deep dive into the pros, cons, available options, and impact on metabolic health https://peterattiamd.com/sugar-substitutes/ https://peterattiamd.com/sugar-substitutes/#comments Tue, 29 Aug 2023 11:00:00 +0000 https://peterattiamd.com/?p=21805 Sugar substitutes offer sweet taste with minimal calories, yet they remain controversial. How well do they solve the problems associated with traditional sugar, and where do they fall short?

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The cases for and against dietary protein for healthy aging https://peterattiamd.com/dietary-protein-and-healthy-aging/ https://peterattiamd.com/dietary-protein-and-healthy-aging/#comments Wed, 26 Jul 2023 22:29:42 +0000 https://peterattiamd.com/?p=21633 An endeavor to settle the debate of high- vs. low-protein diets for increasing lifespan and healthspan

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Does carbohydrate load impact the balance between fat storage and oxidation? https://peterattiamd.com/carbohydrate-load-and-fat-storage/ Sat, 10 Jun 2023 11:00:45 +0000 https://peterattiamd.com/?p=20936 A study investigated the effects of different dietary levels of carbohydrates on mitochondrial respiration, but mechanistic conclusions are premature.

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#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D. https://peterattiamd.com/rhondapatrick2/ https://peterattiamd.com/rhondapatrick2/#comments Mon, 01 May 2023 08:45:03 +0000 https://peterattiamd.com/?p=20763 My perspective has shifted as any scientist that's following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick

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More hype than substance: erythritol and cardiovascular risk https://peterattiamd.com/more-hype-than-substance-erythritol-and-cardiovascular-risk/ Sat, 04 Mar 2023 12:00:03 +0000 https://peterattiamd.com/?p=20412 A newly-published study caught public attention by reporting an association between the common sweetener erythritol and increased risk of heart attack and stroke, but there’s more to the story.

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#242 – AMA #44: Peter’s historical changes in body composition with his evolving dietary, fasting, and training protocols https://peterattiamd.com/ama44/ https://peterattiamd.com/ama44/#comments Mon, 13 Feb 2023 09:45:21 +0000 https://peterattiamd.com/?p=20287 “Trends matter. You're treating what you see, but you're mindful of the trends.” —Peter Attia

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#235 ‒ Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D. https://peterattiamd.com/laynenorton3/ https://peterattiamd.com/laynenorton3/#comments Mon, 19 Dec 2022 09:45:32 +0000 https://peterattiamd.com/?p=19436 Most 40 year olds, 50 year olds, they have pain anyway. So I'd rather be strong and have pain than be weak and have pain.” —Layne Norton

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