Ask Me Anything (AMA) Archives - Peter Attia https://peterattiamd.com/category/ama/ Mon, 17 Feb 2025 18:30:41 +0000 en-US hourly 1 https://peterattiamd.com/wp-content/uploads/2023/04/cropped-apple-icon-32x32.png Ask Me Anything (AMA) Archives - Peter Attia https://peterattiamd.com/category/ama/ 32 32 #336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more https://peterattiamd.com/ama68/ Mon, 17 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32335 It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

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#332 – AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk https://peterattiamd.com/ama67/ Mon, 20 Jan 2025 05:15:00 +0000 https://peterattiamd.com/?p=31901 "As food and beverages undergo more and more processing, it accumulates more and more plastics, probably another argument for limiting processed foods." —Peter Attia

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#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more https://peterattiamd.com/specialama/ Mon, 16 Dec 2024 09:00:00 +0000 https://peterattiamd.com/?p=31196 In this special episode of The Drive, Peter tackles a wide range of listener questions submitted over the past year. The discussion spans essential topics such as exercise—covering grip strength, traveling workouts, and why Peter doesn’t consider exercise an ideal weight-loss strategy—and the top biomarkers everyone should track. He also explores promising new longevity research,…

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328 – AMA #66: Optimizing nutrition for health and longevity: myth of a “best” diet, complexities of nutrition science, and practical steps for building a sustainable diet https://peterattiamd.com/ama66/ Mon, 09 Dec 2024 09:00:00 +0000 https://peterattiamd.com/?p=31036 “There is no discipline of science or engineering for which our magnitude of certainty is so high relative to such poor quality data.” —Peter Attia

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#326 – AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging https://peterattiamd.com/ama65/ https://peterattiamd.com/ama65/#comments Mon, 18 Nov 2024 10:45:00 +0000 https://peterattiamd.com/?p=30417 Most people who are proponents of red light therapy point to cytochrome c oxidase (CCO) as the main target, and therefore the mediating effect of the biologic impact of red light.” —Peter Attia

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#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) – efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape https://peterattiamd.com/ama64/ https://peterattiamd.com/ama64/#comments Mon, 07 Oct 2024 08:45:03 +0000 https://peterattiamd.com/?p=26802 "If you're taking these drugs, really, really pay attention to your protein consumption and your resistance training. . .that's obviously going to be an important part of being on the right side of that body composition curve.” — Peter Attia

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#316 – AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations https://peterattiamd.com/ama63/ https://peterattiamd.com/ama63/#comments Mon, 09 Sep 2024 08:45:36 +0000 https://peterattiamd.com/?p=25774 Genetic sensitivity to DHT appears far more important than absolute DHT level. But. . .lowering DHT is a very important strategy to either preventing or halting hair loss.” —Peter Attia

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#313 – AMA #62: Protein’s impact on appetite and weight management, and uric acid’s link to disease and how to manage levels https://peterattiamd.com/ama62/ https://peterattiamd.com/ama62/#comments Mon, 12 Aug 2024 08:45:11 +0000 https://peterattiamd.com/?p=25622 "The body responds in pretty significant ways to alterations in protein availability.” —Peter Attia

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#308 – AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more https://peterattiamd.com/ama61/ https://peterattiamd.com/ama61/#comments Mon, 01 Jul 2024 08:45:58 +0000 https://peterattiamd.com/?p=25365 This is the beginning of a type of technology that I hope, over the coming decade, can make screening, especially for melanoma, to be a more effective tool.” —Peter Attia

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#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more https://peterattiamd.com/ama60/ https://peterattiamd.com/ama60/#comments Mon, 17 Jun 2024 08:45:49 +0000 https://peterattiamd.com/?p=25279 Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia

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#301 – AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it https://peterattiamd.com/ama59/ https://peterattiamd.com/ama59/#comments Mon, 13 May 2024 08:45:46 +0000 https://peterattiamd.com/?p=25073 Inflammation really becomes chronic once it's persisted for several months, but it can persist for much longer than that.” —Peter Attia

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#297 – AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency https://peterattiamd.com/ama58/ https://peterattiamd.com/ama58/#comments Mon, 08 Apr 2024 08:45:44 +0000 https://peterattiamd.com/?p=24881 “I've seen a lot of cases of iron deficiency. I've seen a lot of cases of iron deficiency anemia. I can't tell you I've seen one that isn't attributable to some combination of … low iron in the diet, poor absorption, or blood loss.” —Peter Attia

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#293 – AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity https://peterattiamd.com/ama57/ https://peterattiamd.com/ama57/#comments Mon, 11 Mar 2024 08:45:45 +0000 https://peterattiamd.com/?p=24745 You want to broaden your portfolio of training.” —Peter Attia

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#289 – AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more https://peterattiamd.com/ama56/ https://peterattiamd.com/ama56/#comments Mon, 12 Feb 2024 09:45:48 +0000 https://peterattiamd.com/?p=24619 "There has been a pretty clear and consistent benefit [to cancer screening] that has been demonstrated, and the exceptions I think have a pretty clear sense of why.” —Peter Attia

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#285 – AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more https://peterattiamd.com/ama55/ https://peterattiamd.com/ama55/#comments Mon, 15 Jan 2024 09:45:54 +0000 https://peterattiamd.com/?p=24395 “Nothing comes close to having a greater impact on the length and quality of your life than your training. And unfortunately, we can't put it in a pill. You’ve got to be able to do it. There's no biohack for it.” —Peter Attia

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#282 – AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more https://peterattiamd.com/ama54/ https://peterattiamd.com/ama54/#comments Mon, 11 Dec 2023 09:45:10 +0000 https://peterattiamd.com/?p=22374 The more deficient you are in magnesium, the more you will be helped by supplementing magnesium.” —Peter Attia

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#279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins https://peterattiamd.com/ama53/ https://peterattiamd.com/ama53/#comments Mon, 13 Nov 2023 09:45:23 +0000 https://peterattiamd.com/?p=22252 It is worth noting, and this is a very important question, that it does not appear that the effect of statins on insulin resistance is a function of lipids being lowered.” —Peter Attia

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#275 – AMA #52: Hormone replacement therapy: practical applications and the role of compounding pharmacies https://peterattiamd.com/ama52/ https://peterattiamd.com/ama52/#comments Mon, 16 Oct 2023 08:45:51 +0000 https://peterattiamd.com/?p=22139 The sum total of lives that have been saved due to less breast cancer as a result from the lack of HRT for the past 20 years is exactly zero.” —Peter Attia

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#271 – AMA #51: Understanding and improving your metabolic health https://peterattiamd.com/ama51/ https://peterattiamd.com/ama51/#comments Mon, 18 Sep 2023 08:45:10 +0000 https://peterattiamd.com/?p=22005 Zone 2 output is arguably the most important functional test we have of metabolic health.” —Peter Attia

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#266 – AMA #50: Genetics: how they impact disease risk, what you can do about it, testing, and more https://peterattiamd.com/ama50/ https://peterattiamd.com/ama50/#comments Mon, 14 Aug 2023 08:45:24 +0000 https://peterattiamd.com/?p=21742 With how much uncertainty there is in genetic testing, I just think everybody needs to be thoughtful about it before they do it.” —Peter Attia

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#262 – AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health https://peterattiamd.com/ama49/ https://peterattiamd.com/ama49/#comments Mon, 17 Jul 2023 08:45:41 +0000 https://peterattiamd.com/?p=21070 [Heart rate recovery] is one of the metrics that we should care about just as we care about VO2 max and just as we care about resting heart rate.” —Peter Attia

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#258 – AMA #48: Blood pressure—how to measure, manage, and treat high blood pressure https://peterattiamd.com/ama48/ https://peterattiamd.com/ama48/#comments Mon, 12 Jun 2023 08:45:03 +0000 https://peterattiamd.com/?p=20934 If you care about your brain, if you care about your heart and if you care about your kidneys, you need low blood pressure. I think we can say that as confidently as we can say almost anything in medicine.” —Peter Attia

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#254 – AMA #47: Cold therapy: pros, cons, and its impact on longevity https://peterattiamd.com/ama47/ https://peterattiamd.com/ama47/#comments Mon, 15 May 2023 08:45:10 +0000 https://peterattiamd.com/?p=20816 If we're talking about [activating brown adipose tissue] as a solution for overweight or obesity in adults, it's not a needle mover.” —Peter Attia

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#251 – AMA #46: Optimizing brain health: Alzheimer’s disease risk factors, APOE, prevention strategies, and more https://peterattiamd.com/ama46/ https://peterattiamd.com/ama46/#comments Mon, 17 Apr 2023 08:45:56 +0000 https://peterattiamd.com/?p=20699 The bottom line here is the earlier you were diagnosed with type 2 diabetes, the higher your risk of dementia.” —Peter Attia

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