Brain Archives - Peter Attia Thu, 27 Feb 2025 20:36:24 +0000 en-US hourly 1 https://peterattiamd.com/wp-content/uploads/2023/04/cropped-apple-icon-32x32.png Brain Archives - Peter Attia 32 32 #334 – Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D. https://peterattiamd.com/tomdayspring7/ Mon, 03 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32179 Cholesterol is almost certainly the most important molecule in the brain.” —Tom Dayspring

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Shingles and brain health: an emerging link or healthy user bias? https://peterattiamd.com/shingles-and-brain-health/ https://peterattiamd.com/shingles-and-brain-health/#comments Sat, 23 Nov 2024 12:00:00 +0000 https://peterattiamd.com/?p=30639 Several research articles have been circulating in the news, prompting excitement about the supposed ability of the shingles vaccine to prevent cognitive decline, but is there a causal link?

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#321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D. https://peterattiamd.com/annalembke/ https://peterattiamd.com/annalembke/#comments Mon, 14 Oct 2024 08:45:48 +0000 https://peterattiamd.com/?p=27012 When we do things intentionally that are physically or mentally challenging for us, our body senses injury and up regulates feel good neurotransmitters. . .so we get our dopamine indirectly by paying for it upfront.” —Anna Lembke

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#319 ‒ Peter’s key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2 https://peterattiamd.com/qps2/ https://peterattiamd.com/qps2/#comments Mon, 30 Sep 2024 08:45:49 +0000 https://peterattiamd.com/?p=25847 In humans, klotho is indeed a longevity gene. More klotho from the gene means longer life, better cognition. Take it away, shorter life, worse cognition.” —Peter Attia

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#312 – A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D. https://peterattiamd.com/georgebrooks/ https://peterattiamd.com/georgebrooks/#comments Mon, 05 Aug 2024 08:45:28 +0000 https://peterattiamd.com/?p=25578 Lactate is not just an innocent bystander. It's a participant in the process of powering muscle, in fact, all cells.” —George Brooks

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#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more https://peterattiamd.com/ama60/ https://peterattiamd.com/ama60/#comments Mon, 17 Jun 2024 08:45:49 +0000 https://peterattiamd.com/?p=25279 Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia

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#303 – A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer’s disease | Dena Dubal, M.D., Ph.D. https://peterattiamd.com/denadubal/ https://peterattiamd.com/denadubal/#comments Mon, 27 May 2024 08:45:09 +0000 https://peterattiamd.com/?p=25182 I have this dream that people might be able someday to benefit from klotho, this factor that naturally circulates in our body, that helps with longevity, that helps with other organ systems and enhances the brain.” —Dena Dubal

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Research Worth Sharing, March 2024 Edition https://peterattiamd.com/research-worth-sharing-march-2024/ Sat, 30 Mar 2024 11:00:38 +0000 https://peterattiamd.com/?p=24849 Organ-specific aging, a blood-based test for brain tumors, avoiding bananas in smoothies, stair-climbing tests for frailty, and omega-3 intake and CVD

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Is the frequency of menopausal symptoms an early barometer for later-in-life brain health? https://peterattiamd.com/hrt-vasomotor-symptoms-and-white-matter-hypsersensitivity/ Sat, 28 Oct 2023 11:00:37 +0000 https://peterattiamd.com/?p=22189 More than “bothersome”: Frequent menopausal hot flashes during sleep are associated with greater white matter hyperintensity volume

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Could a psoriasis drug find new purpose in treating alcohol use disorder? https://peterattiamd.com/apremilast-for-alcohol-use-disorder/ Sat, 21 Oct 2023 11:00:36 +0000 https://peterattiamd.com/?p=22140 Recent pilot research suggests that the psoriasis drug apremilast may have promise in curbing excessive drinking in those with alcohol use disorder.

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Improving memory with transcranial neuromodulation https://peterattiamd.com/improving-memory-with-transcranial-neuromodulation/ Sat, 26 Aug 2023 11:00:00 +0000 https://peterattiamd.com/?p=21865 Research shows that noninvasive neuromodulation can improve performance in memory tasks. Is this technique simply a research tool, or is it a therapy of the future?

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#263 ‒ Concussions and head trauma: symptoms, treatment, and recovery | Micky Collins, Ph.D. https://peterattiamd.com/mickycollins/ https://peterattiamd.com/mickycollins/#comments Mon, 24 Jul 2023 08:45:16 +0000 https://peterattiamd.com/?p=21619 If you bring me a patient with concussion, I can pretty much tell you I can get that patient better. There are highly effective treatments with this injury.” —Micky Collins

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#262 – AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health https://peterattiamd.com/ama49/ https://peterattiamd.com/ama49/#comments Mon, 17 Jul 2023 08:45:41 +0000 https://peterattiamd.com/?p=21070 [Heart rate recovery] is one of the metrics that we should care about just as we care about VO2 max and just as we care about resting heart rate.” —Peter Attia

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#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D. https://peterattiamd.com/tommywood/ https://peterattiamd.com/tommywood/#comments Mon, 05 Jun 2023 08:45:36 +0000 https://peterattiamd.com/?p=20919 "If you're trying to maintain a basic set of cognitive functions, [it is important] to actively work on ways to increase headroom, increase absolute capacity throughout the lifespan. Because at some point capacity will decrease, but you want to push that out as far as you can." —Tommy Wood

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#251 – AMA #46: Optimizing brain health: Alzheimer’s disease risk factors, APOE, prevention strategies, and more https://peterattiamd.com/ama46/ https://peterattiamd.com/ama46/#comments Mon, 17 Apr 2023 08:45:56 +0000 https://peterattiamd.com/?p=20699 The bottom line here is the earlier you were diagnosed with type 2 diabetes, the higher your risk of dementia.” —Peter Attia

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#249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D. https://peterattiamd.com/andrewhuberman/ https://peterattiamd.com/andrewhuberman/#comments Mon, 03 Apr 2023 08:45:47 +0000 https://peterattiamd.com/?p=20639 I want to communicate the beauty and utility of biology. I want to do that by being a teacher and a storyteller.” —Andrew Huberman

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Understanding nature’s effects on stress requires more than intuition https://peterattiamd.com/natures-effects-on-stress/ Sat, 17 Dec 2022 12:00:49 +0000 https://peterattiamd.com/?p=19441 A recent study investigated how nature walks impact brain regions involved in stress responses but trips on its own assumptions

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#220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D. https://peterattiamd.com/celiamorgan/ https://peterattiamd.com/celiamorgan/#comments Mon, 29 Aug 2022 08:45:52 +0000 https://peterattiamd.com/?p=18702 You could time your psychological therapy when your brain is most plastic, most able to learn new things.” —Celia Morgan

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#215 – The gut-brain connection | Michael Gershon, M.D. https://peterattiamd.com/michaelgershon/ https://peterattiamd.com/michaelgershon/#comments Mon, 25 Jul 2022 08:45:05 +0000 https://peterattiamd.com/?p=18507 The reason I call it “The Second Brain” is that, like the brain in the head, the nervous system of the gut is able to function and control reflexes and behavior independently of any influence from the brain or spinal cord.” —Michael Gershon

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Low LDL cholesterol and neural development https://peterattiamd.com/low-ldl-cholesterol-and-neural-development/ Sat, 05 Feb 2022 15:00:43 +0000 https://peterattiamd.com/?p=16718 Why LDL-lowering treatments don’t pit head against heart

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#190 – Paul Conti, M.D.: How to heal from trauma and break the cycle of shame https://peterattiamd.com/paulconti3/ https://peterattiamd.com/paulconti3/#comments Mon, 10 Jan 2022 09:45:34 +0000 https://peterattiamd.com/?p=16513 “Trauma changes the instrument that we use to understand our trauma. It's changing our brain.” —Paul Conti

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#182 – David Nutt: Psychedelics & Recreational Drugs https://peterattiamd.com/davidnutt/ https://peterattiamd.com/davidnutt/#comments Mon, 01 Nov 2021 08:45:49 +0000 https://peterattiamd.com/?p=16279 “It turns out that the drugs that have been most vilified and which we've been taught are the most dangerous, turned out to be the least dangerous.” —David Nutt

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Does low cholesterol cause cognitive impairment? Part II https://peterattiamd.com/does-low-cholesterol-cause-cognitive-impairment-part-ii/ https://peterattiamd.com/does-low-cholesterol-cause-cognitive-impairment-part-ii/#comments Sun, 26 Sep 2021 09:45:11 +0000 https://peterattiamd.com/?p=16168 Safety of lipid-lowering therapy

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Does low cholesterol cause cognitive impairment? Part I https://peterattiamd.com/does-low-cholesterol-cause-cognitive-impairment-part-i/ https://peterattiamd.com/does-low-cholesterol-cause-cognitive-impairment-part-i/#comments Sun, 19 Sep 2021 09:45:24 +0000 https://peterattiamd.com/?p=16127 Safety of lipid-lowering therapy

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