Cholesterol Archives - Peter Attia https://peterattiamd.com/category/risks/cholesterol/ Fri, 07 Mar 2025 23:26:03 +0000 en-US hourly 1 https://peterattiamd.com/wp-content/uploads/2023/04/cropped-apple-icon-32x32.png Cholesterol Archives - Peter Attia https://peterattiamd.com/category/risks/cholesterol/ 32 32 #338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4 https://peterattiamd.com/qps4/ Mon, 03 Mar 2025 05:15:00 +0000 https://peterattiamd.com/?p=32932 “You need to tackle the foe [type 2 diabetes] by addressing more than one leg of the stool at a time.” —Peter Attia

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]]> #336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more https://peterattiamd.com/ama68/ Mon, 17 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32335 “It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

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]]> #334 – Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D. https://peterattiamd.com/tomdayspring7/ Mon, 03 Feb 2025 05:15:00 +0000 https://peterattiamd.com/?p=32179 “Cholesterol is almost certainly the most important molecule in the brain.” —Tom Dayspring

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]]> Coronary atherosclerosis is a silent killer, but we have tools to stop it https://peterattiamd.com/tools-to-stop-cad/ Sat, 17 Aug 2024 11:00:06 +0000 https://peterattiamd.com/?p=25657 A new study reveals that the prevalence of atherosclerosis is alarmingly high among asymptomatic adults classified as “low risk” and underscores the importance of lipid-lowering therapies for avoiding atherosclerosis progression and mortality

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]]> #311 ‒ Longevity 101: a foundational guide to Peter’s frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more https://peterattiamd.com/longevity101/ https://peterattiamd.com/longevity101/#comments Mon, 29 Jul 2024 08:45:32 +0000 https://peterattiamd.com/?p=25544 “I would say three-quarters of the benefits you can get towards a longer life, come solely from pursuing better health.” —Peter Attia

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]]> https://peterattiamd.com/longevity101/feed/ 7 #306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more https://peterattiamd.com/ama60/ https://peterattiamd.com/ama60/#comments Mon, 17 Jun 2024 08:45:49 +0000 https://peterattiamd.com/?p=25279 “Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia

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]]> https://peterattiamd.com/ama60/feed/ 10 “The cholesterol paradox”: a catchy phrase for an idea with no substance https://peterattiamd.com/issues-with-the-cholesterol-paradox/ Sat, 27 May 2023 11:00:49 +0000 https://peterattiamd.com/?p=20888 A recent study reported that hypercholesterolemia is associated with reduced mortality, but it falls short of upsetting conventional wisdom

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]]> The genetics of PCSK9i nonresponders https://peterattiamd.com/genetics-of-pcsk9i-nonresponders/ Sat, 01 Oct 2022 11:00:43 +0000 https://peterattiamd.com/?p=18866 A recent case study shines light on why some individuals are resistant to PCSK9 inhibitors. 

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]]> Heart Disease: Labs & Diagnostic Tests https://peterattiamd.com/heart-disease-labs-diagnostic-tests/ Tue, 30 Aug 2022 12:00:26 +0000 https://peterattiamd.com/?p=18446 This video clip is from episode #203 — AMA #34: What causes heart disease? — originally released on April 18, 2022. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode…

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]]> First Case of Human PCSK9 Gene-Editing https://peterattiamd.com/pcsk9-gene-editing/ Sat, 06 Aug 2022 11:00:01 +0000 https://peterattiamd.com/?p=18586 Ultimately, the long-term benefits of lowering apoB through a one-time treatment may make this not only a viable future option, but potentially an intervention that could change preventive cardiovascular medicine.

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]]> Cumulative effects of LDL-C reduction in mitigating cardiovascular risk https://peterattiamd.com/cumulative-effects-of-ldl-c-reduction-in-mitigating-cardiovascular-risk/ Sat, 09 Jul 2022 14:00:15 +0000 https://peterattiamd.com/?p=18441 Atherosclerotic cardiovascular disease (ASCVD) is currently the leading cause of death in the U.S. One of the most effective ways to reduce risk of ASCVD mortality is reduction of apoB particle number, typically estimated by LDL cholesterol (LDL-C) concentrations.

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]]> Lp(a) and CVD risk & clinical tests to measure Lp(a) https://peterattiamd.com/lpa-and-cvd-risk-clinical-tests-to-measure-lpa/ Mon, 27 Jun 2022 22:33:14 +0000 https://peterattiamd.com/?p=18448 This video clip is from episode #210 – Lp(a) and its impact on heart disease with Benoît Arsenault, Ph.D., originally released on June 13, 2022.

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]]> Peter’s approach to managing patients with high Lp(a) https://peterattiamd.com/managing-patients-with-high-lpa/ Wed, 15 Jun 2022 12:00:09 +0000 https://peterattiamd.com/?p=18285 This video is a clip from episode #210 – Lp(a) and its impact on heart disease with Benoît Arsenault, Ph.D., originally released on June 13, 2022.

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]]> #210 – Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D. https://peterattiamd.com/benoitarsenault/ https://peterattiamd.com/benoitarsenault/#comments Mon, 13 Jun 2022 08:45:12 +0000 https://peterattiamd.com/?p=18206 “I think we should advise people to measure Lp(a); that would be a gigantic step.” —Benoît Arsenault

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]]> https://peterattiamd.com/benoitarsenault/feed/ 6 For triglycerides, “normal” may not be “optimal” https://peterattiamd.com/triglyceride-levels-cardiovascular-risk/ Sat, 14 May 2022 14:00:16 +0000 https://peterattiamd.com/?p=18015 How do triglyceride levels relate to cardiovascular risk?

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]]> Intro to lipids & lipoproteins: why there is no ‘bad’ or ‘good’ cholesterol https://peterattiamd.com/why-there-is-no-bad-or-good-cholesterol/ https://peterattiamd.com/why-there-is-no-bad-or-good-cholesterol/#comments Wed, 11 May 2022 14:00:03 +0000 https://peterattiamd.com/?p=17922 I recently posted on Twitter about my frustration with the way the press writes about “good” and “bad” cholesterol, and several people then asked me for the TL;DR version of ‘cholesterol 101.’ As I realize not everyone can take the time to go through the many hours of cholesterol content we have on The Drive,…

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]]> https://peterattiamd.com/why-there-is-no-bad-or-good-cholesterol/feed/ 15 #203 – AMA #34: What Causes Heart Disease? https://peterattiamd.com/ama34/ https://peterattiamd.com/ama34/#comments Mon, 18 Apr 2022 08:45:38 +0000 https://peterattiamd.com/?p=17687 “Not everybody dies from atherosclerosis, but… everybody dies with it.” — Peter Attia

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]]> https://peterattiamd.com/ama34/feed/ 15 When CAC Tests Are Useful and When They Are Not https://peterattiamd.com/when-cac-tests-are-useful-and-when-they-are-not/ Fri, 15 Apr 2022 17:45:24 +0000 https://peterattiamd.com/?p=17795 This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk, originally released on November 29, 2021.

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]]> Peter on why early prevention of atherosclerosis is critical https://peterattiamd.com/peter-on-why-early-prevention-of-atherosclerosis-is-critical/ Fri, 15 Apr 2022 17:35:36 +0000 https://peterattiamd.com/?p=17793 This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk, originally released on November 29, 2021.

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]]> Preventing Atherosclerosis: 2 Fatal Flaws with the “10 Year Risk” Approach https://peterattiamd.com/preventing-atherosclerosis-flaws-with-the-10-year-risk-approach/ Fri, 15 Apr 2022 17:28:53 +0000 https://peterattiamd.com/?p=17791 This video clip is from episode #185 – Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk, originally released on November 29, 2021.  

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]]> Peter on how early and aggressive lowering of apoB could change the course of ASCVD https://peterattiamd.com/early-and-aggressive-lowering-of-apob/ https://peterattiamd.com/early-and-aggressive-lowering-of-apob/#comments Fri, 15 Apr 2022 17:20:44 +0000 https://peterattiamd.com/?p=17789 This audio clip is from episode #202 – Peter on nutrition, disease prevention, sleep, and more, originally released on April 11, 2022.

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]]> https://peterattiamd.com/early-and-aggressive-lowering-of-apob/feed/ 2 Why a recent study hasn’t shaken my faith in statins https://peterattiamd.com/why-a-recent-study-hasnt-shaken-my-faith-in-statins/ Sun, 03 Apr 2022 00:00:42 +0000 https://peterattiamd.com/?p=17636 A rebuttal of Byrne et al.

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]]> #196 – AMA #32: Exercise, squats, deadlifts, BFR, and TRT https://peterattiamd.com/ama32/ https://peterattiamd.com/ama32/#comments Mon, 21 Feb 2022 09:45:52 +0000 https://peterattiamd.com/?p=16801 “You have to differentiate between signal and noise. . .it's easy to say testosterone causes heart disease just like it's easy to say estrogen causes breast cancer. But if you're actually going to go through all of the data. . .I think it becomes very difficult to make that case.” —Peter Attia

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]]> https://peterattiamd.com/ama32/feed/ 13 Low LDL cholesterol and neural development https://peterattiamd.com/low-ldl-cholesterol-and-neural-development/ Sat, 05 Feb 2022 15:00:43 +0000 https://peterattiamd.com/?p=16718 Why LDL-lowering treatments don’t pit head against heart

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