How to Prevent & Reverse Insulin Resistance | Peter Attia, M.D.

#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4

Peter Attia — Mon, 03 Mar 2025 05:15:00 +0000

“You need to tackle the foe [type 2 diabetes] by addressing more than one leg of the stool at a time.” —Peter Attia

The post #338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4 appeared first on Peter Attia.

#336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

Peter Attia — Mon, 17 Feb 2025 05:15:00 +0000

“It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

The post #336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more appeared first on Peter Attia.

Research Worth Sharing, December 2024 Edition

Peter Attia — Sat, 21 Dec 2024 12:00:00 +0000

Type 2 diabetes in youths, extending organ viability, preventative ovary removal, “dark genome” therapeutics, and vascular impacts on physical decline

The post Research Worth Sharing, December 2024 Edition appeared first on Peter Attia.

#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more

Peter Attia — Mon, 16 Dec 2024 09:00:00 +0000

In this special episode of The Drive, Peter tackles a wide range of listener questions submitted over the past year. The discussion spans essential topics such as exercise—covering grip strength, traveling workouts, and why Peter doesn’t consider exercise an ideal weight-loss strategy—and the top biomarkers everyone should track. He also explores promising new longevity research,…

The post #329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more appeared first on Peter Attia.

#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.

Peter Attia — Mon, 04 Nov 2024 09:45:31 +0000

“I still believe that a nutritional approach to weight loss without physical activity or exercise prescribed is not a good strategy. We should implement both and try to have people enjoying the exercise.” —Eric Ravussin

The post #324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D. appeared first on Peter Attia.

#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) – efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape

Peter Attia — Mon, 07 Oct 2024 08:45:03 +0000

"If you're taking these drugs, really, really pay attention to your protein consumption and your resistance training. . .that's obviously going to be an important part of being on the right side of that body composition curve.” — Peter Attia

The post #320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) – efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape appeared first on Peter Attia.

Back on the merry-go-round of bad science regarding meat consumption

Peter Attia — Sat, 24 Aug 2024 11:00:01 +0000

A new observational study has reported positive associations between meat intake and type 2 diabetes risk, but let’s repeat: correlation is not causation.

The post Back on the merry-go-round of bad science regarding meat consumption appeared first on Peter Attia.

#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.

Peter Attia — Mon, 19 Aug 2024 08:45:11 +0000

“I think we really need a radically different public health paradigm.” —David Allison

The post #314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D. appeared first on Peter Attia.

#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more

Peter Attia — Mon, 17 Jun 2024 08:45:49 +0000

“Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia

The post #306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more appeared first on Peter Attia.

“DNA diets” are still a long way off from offering an easier route to weight loss

Peter Attia — Sat, 16 Mar 2024 11:00:53 +0000

A recent study reports that leveraging genetics to inform diet choice is ineffective in promoting weight loss beyond the effects of calorie restriction alone

The post “DNA diets” are still a long way off from offering an easier route to weight loss appeared first on Peter Attia.

Is low-to-moderate alcohol consumption beneficial for longevity?

Peter Attia — Wed, 03 Jan 2024 12:00:00 +0000

There is a common belief that low-to-moderate consumption of alcohol has unique health benefits. What does the evidence show?

The post Is low-to-moderate alcohol consumption beneficial for longevity? appeared first on Peter Attia.

#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.

Peter Attia — Mon, 18 Dec 2023 09:45:06 +0000

“You start out almost like a blank slate, you get a lot more diverse, and then as we age, you start to lose that diversity and therefore some key functions in the microbiome.” —Colleen Cutcliffe

The post #283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D. appeared first on Peter Attia.

#279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins

Peter Attia — Mon, 13 Nov 2023 09:45:23 +0000

“It is worth noting, and this is a very important question, that it does not appear that the effect of statins on insulin resistance is a function of lipids being lowered.” —Peter Attia

The post #279 – AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins appeared first on Peter Attia.

Does carbohydrate load impact the balance between fat storage and oxidation?

Peter Attia — Sat, 10 Jun 2023 11:00:45 +0000

A study investigated the effects of different dietary levels of carbohydrates on mitochondrial respiration, but mechanistic conclusions are premature.

The post Does carbohydrate load impact the balance between fat storage and oxidation? appeared first on Peter Attia.

#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.

Peter Attia — Mon, 01 May 2023 08:45:03 +0000

“My perspective has shifted as any scientist that's following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick

The post #252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D. appeared first on Peter Attia.

Is a recent clinical trial enough to support the use of semaglutide in treating adolescent obesity?

Peter Attia — Sat, 22 Apr 2023 11:00:52 +0000

The imperative for effective weight management strategies in children and teens is clear, but in our desperation for effective obesity treatments, are we allowing ourselves to be too shortsighted on testing?

The post Is a recent clinical trial enough to support the use of semaglutide in treating adolescent obesity? appeared first on Peter Attia.

The five main tools for managing blood glucose numbers

Peter Attia — Tue, 16 Aug 2022 13:00:17 +0000

This clip is from AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions, originally released on August 23, 2021.

The post The five main tools for managing blood glucose numbers appeared first on Peter Attia.

#212 – The neuroscience of obesity | Stephan Guyenet, Ph.D.

Peter Attia — Mon, 27 Jun 2022 08:45:27 +0000

“This system works better at protecting against fat loss than it does against fat gain.” —Stephan Guyenet

The post #212 – The neuroscience of obesity | Stephan Guyenet, Ph.D. appeared first on Peter Attia.

Is natural sugar from fruit just as ‘bad’ as added sugar?

Peter Attia — Fri, 24 Jun 2022 19:38:26 +0000

This video clip is taken from episode #194 – How Fructose Drives Metabolic Disease with Rick Johnson, M.D., originally released on February 7, 2022.

The post Is natural sugar from fruit just as ‘bad’ as added sugar? appeared first on Peter Attia.

Metabolic dysfunction case study and a framework for metabolic health

Peter Attia — Wed, 22 Jun 2022 12:00:43 +0000

This audio clip is from “Ask Me Anything” (AMA) episode #15 — Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more, originally released on August 17, 2020. If you’re a member, you can now listen to this full episode on your private RSS feed or on our website. If you are not a member, learn more about the how to become…

The post Metabolic dysfunction case study and a framework for metabolic health appeared first on Peter Attia.

How metabolic health impacts your ‘optimal’ diet

Peter Attia — Tue, 21 Jun 2022 12:00:15 +0000

This audio clip is from “Ask Me Anything” (AMA) episode #36 — all things fruits and vegetables, originally released on June 20, 2022. If you’re a member, you can now listen to this full episode on your private RSS feed or on our website. If you are not a member, learn more about the how to become a member and the…

The post How metabolic health impacts your ‘optimal’ diet appeared first on Peter Attia.

#211 – AMA #36: Fruits & vegetables—everything you need to know

Peter Attia — Mon, 20 Jun 2022 08:45:41 +0000

"There's also a very significant cultural and social component to this thing as well. So I think that's where the tribalism comes from around nutrition.” —Peter Attia

The post #211 – AMA #36: Fruits & vegetables—everything you need to know appeared first on Peter Attia.

Why you should stop drinking sugar

Peter Attia — Wed, 15 Jun 2022 21:33:58 +0000

This video clip is taken from Podcast #194 – How Fructose Drives Metabolic Disease with Rick Johnson, M.D., originally released on February 7, 2022.

The post Why you should stop drinking sugar appeared first on Peter Attia.

Breaking down VO2 max: Definition, history, why it plateaus, and whether it really matters

Peter Attia — Mon, 16 May 2022 23:39:35 +0000

This video clip is from #151 – Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance, originally released on March 1, 2021.

The post Breaking down VO2 max: Definition, history, why it plateaus, and whether it really matters appeared first on Peter Attia.