Longevity Archives - Peter Attia

#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4

Peter Attia — Mon, 03 Mar 2025 05:15:00 +0000

“You need to tackle the foe [type 2 diabetes] by addressing more than one leg of the stool at a time.” —Peter Attia

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Metformin as a potential longevity medication: where do we stand?

Peter Attia — Wed, 26 Feb 2025 13:00:00 +0000

Hype over metformin’s longevity effects has waxed and waned, with a recent boost from a high-profile study. How should we think about this evidence?

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#336 – AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more

Peter Attia — Mon, 17 Feb 2025 05:15:00 +0000

“It's the calorie restriction that provides the greatest benefit. How you go about achieving it is really a function of your style.” —Peter Attia

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#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Ph.D., Matt Kaeberlein, Ph.D., Richard Miller, M.D., Ph.D.

Peter Attia — Mon, 27 Jan 2025 05:15:00 +0000

“The notion that aging is not malleable, though wrong and provably wrong, is still the overwhelming opinion even of reasonably educated scientists and certainly of the lay public.” ‒ Rich Miller

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The endless possibilities of living well in your marginal decade

Peter Attia — Sat, 04 Jan 2025 12:00:00 +0000

A spotlight on a few inspirational people doing amazing things in their 80s, 90s, and beyond

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Research Worth Sharing, December 2024 Edition

Peter Attia — Sat, 21 Dec 2024 12:00:00 +0000

Type 2 diabetes in youths, extending organ viability, preventative ovary removal, “dark genome” therapeutics, and vascular impacts on physical decline

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#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more

Peter Attia — Mon, 16 Dec 2024 09:00:00 +0000

In this special episode of The Drive, Peter tackles a wide range of listener questions submitted over the past year. The discussion spans essential topics such as exercise—covering grip strength, traveling workouts, and why Peter doesn’t consider exercise an ideal weight-loss strategy—and the top biomarkers everyone should track. He also explores promising new longevity research,…

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Evaluating NAD and NAD precursors for health and longevity

Peter Attia — Wed, 11 Dec 2024 23:07:16 +0000

NAD and its precursors – mainly NR and NMN – have garnered attention for numerous purported benefits, but which are supported by evidence?

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Oldies-But-Goodies, December 2024 Edition

Peter Attia — Sat, 30 Nov 2024 12:00:00 +0000

A collection of past newsletters on topics including hearing loss prevention, a randomized trial on exercise and lifespan, using a cognitive bias to improve goal achievement, air pollution, and the impact of dietary protein on muscle protein synthesis

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#326 – AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging

Peter Attia — Mon, 18 Nov 2024 10:45:00 +0000

“Most people who are proponents of red light therapy point to cytochrome c oxidase (CCO) as the main target, and therefore the mediating effect of the biologic impact of red light.” —Peter Attia

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What can we learn from “blue zones”?

Peter Attia — Tue, 12 Nov 2024 12:00:00 +0000

Certain areas of the world have been reported as having disproportionately high numbers of centenarians. What explains these patterns, and what – if anything – do they reveal about the “secrets” to long life?

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#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3

Peter Attia — Mon, 11 Nov 2024 09:45:29 +0000

“I suspect that that will be the challenge of the next decade or two. It'll be less about what is technically possible and more about what is ethically defensible.” —Peter Attia

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Radical extension of the human lifespan, science fiction or reality?

Peter Attia — Sat, 09 Nov 2024 12:00:58 +0000

Humanity may be reaching the limits of lifespan extension that are possible through treatment of chronic disease, but the door is still open for future advances in aging biology itself

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#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.

Peter Attia — Mon, 04 Nov 2024 09:45:31 +0000

“I still believe that a nutritional approach to weight loss without physical activity or exercise prescribed is not a good strategy. We should implement both and try to have people enjoying the exercise.” —Eric Ravussin

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Failure of resveratrol to improve metabolic health is another nail in the coffin for the alleged “anti-aging” compound

Peter Attia — Sat, 26 Oct 2024 11:00:12 +0000

A recent meta-analysis of randomized trials assessed the performance of resveratrol in improving various metrics of metabolic health

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#322 – Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.

Peter Attia — Mon, 21 Oct 2024 08:45:51 +0000

“Bone is a ‘use it or lose it’ tissue.” —Belinda Beck

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Do humans age in distinct rapid bursts instead of gradually over time?

Peter Attia — Sat, 05 Oct 2024 11:00:41 +0000

A recent study makes use of multi-omics data to establish patterns of human aging, but results have dubious relevance on an individual scale

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Cold therapy: the facts, the myths, and the how-to

Peter Attia — Thu, 26 Sep 2024 08:00:00 +0000

Forms of cold therapy have been used for generations for a number of alleged health benefits, but which are supported by evidence?

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#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.

Peter Attia — Mon, 16 Sep 2024 08:45:24 +0000

“One of the most important qualities of a physician is humility, knowing your limits, and having the self-awareness that you could be wrong.” —Marty Makary

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Is interleukin-11 a promising new target for lifespan-extending interventions?

Peter Attia — Sat, 07 Sep 2024 11:00:45 +0000

A recent study reports impressive results in male and female mice with anti-IL-11 therapy

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#311 ‒ Longevity 101: a foundational guide to Peter’s frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more

Peter Attia — Mon, 29 Jul 2024 08:45:32 +0000

“I would say three-quarters of the benefits you can get towards a longer life, come solely from pursuing better health.” —Peter Attia

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#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more

Peter Attia — Mon, 17 Jun 2024 08:45:49 +0000

“Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia

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#300 – Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?

Peter Attia — Mon, 06 May 2024 08:45:12 +0000

“The probability that having a high VO2 max, high muscle mass, and high muscle strength are going to increase the length of your life and improve the quality of your life. . .is so high that to act in disregard of that is irresponsible.” —Peter Attia

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More “hack” than “bio”: why biohacking sends the wrong messages about the pursuit of health and longevity

Peter Attia — Sat, 20 Apr 2024 11:00:07 +0000

Distracting from the approaches that matter

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